Multiscale models for biological systems
نویسندگان
چکیده
منابع مشابه
Multiscale models for biological systems
a r t i c l e i n f o Life, amazingly rich in diversity of shapes and functions, explores the limits of extreme complexity in nature. In this review we shall discuss in general terms the use of multiscale mathematical and computer models to study the dynamics of biological systems. These models permit integration of the rapidly expanding knowledge concerning the molecular basis of biology and i...
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It is argued that multiscale approaches are necessary for an explanatory modeling of biological systems. A first step, besides common to the multiscale modeling of physical and living systems, is a bottom-up integration based on the notions of effective parameters and minimal models. Top-down effects can be accounted for in terms of effective constraints and inputs. Biological systems are essen...
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A consensus has recently emerged that further progress in understanding human physiopathology will demand integrative views of biological systems. In this context, complex systems and related interdisciplinary approaches of biology are expected to help. The aim of this collective paper is basically to provide a starting point for further discussions and interactions within the community of comp...
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ژورنال
عنوان ژورنال: Current Opinion in Colloid & Interface Science
سال: 2010
ISSN: 1359-0294
DOI: 10.1016/j.cocis.2009.04.004